Original Articles - Accepted preprints

Accepted Preprints are authors' manuscripts of accepted articles, prior to copyediting, page layout and proofing, available immediately on the day of acceptance for publication.

Qingwu Liao, Wenan Chen, Zhufeng Tong, Mingming Xue, Tianwen Gu, Ying Yuan, Zhenju Song and Zhengang Tao: Shufeng Jiedu capsules protect rats against LPS-induced acute lung injury via activating NRF2-associated antioxidant pathway. Manuscript

Chihiro Koike, Koji Okudela, Mai Matsumura, Hideaki Mitsui, Takehisa Suzuki, Hiromasa Arai, Toshiaki Kataoka, Yoshihiro Ishikawa, Shigeaki Umeda, Yoko Tateishi and Kenichi Ohashi: Frequent DYRK2 gene amplification in micropapillary element of lung adenocarcinoma - an implication in progression in EGFR-mutated lung adenocarcinoma. Manuscript

Nermine M. Abd Raboh, Sarah A. Hakim and Rasha M. Abd El Atti: Implications of androgen receptor and FUS expression on tumor progression in urothelial carcinoma. Manuscript

Yunzhu Li, Jiayu Li and Jiman Li: Two updates on oesophagogastric junction adenocarcinoma from the fifth WHO classification: alteration of definition and emphasis on HER2 test. Manuscript

Hong-Yi Zhou, Fan Jiang, Zhong Cao, Qi-Yun Shen, Yu-Jing Feng and Zhen-Huan Hou: Propofol protects PC12 cells from cobalt chloride -induced injury by mediating miR-134. Manuscript

Pei Wu, Jinou Wang, Xiaoyun Mao, Huimian Xu and Zhi Zhu: PDCD4 regulates apoptosis in human peritoneal mesothelial cells and promotes gastric cancer peritoneal metastasis. Manuscript

Wei-Wei Bao, Xing-Hui Qu, Yan Ma, You-Ling Shi, Guang-Ming Pang and Lei Yang: MiR-590-5p regulates cell proliferation, apoptosis, migration and invasion in oral squamous cell carcinoma by targeting RECK. Manuscript

Ya-Kun Liu, Ya-Jing Jia, Shi-Hao Liu, Hong-Jie Shi and Jing Ma: Low expression of FXYD5 reverses the cisplatin resistance of epithelial ovarian cancer cells. Manuscript

Brandon J. Rose, Jeffery A. Weyand, Brady Liu, Jacob F. Smith, Brian R. Perez, J. Christian Clark, Michael Goodman, Kelsey M. Hirschi Budge, Dennis L. Eggett, Juan A. Arroyo, Paul R. Reynolds and David L. Kooyman: Exposure to second-hand cigarette smoke exacerbates the progression of osteoarthritis in a surgical induced murine model. Manuscript

Qinghui Ji, Xiaofeng Qiao, Yongxiang Liu and Dawei Wang: Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes. Manuscript

Peter Ella-tongwiis, Alexander Makanga, Iqbal Shergill and Stephen Fôn Hughes: Optimisation and validation of immunohistochemistry protocols for cancer research. Manuscript

Sang-Hwan Kim and Jong-Taek Yoon: Morphological changes in mouse ovary due to hormonal hypersecretion and matrix metalloproteinase -2 activity. Manuscript

Abderrahman Ouban: Expression of Claudin-1 in Laryngeal Squamous Cell Carcinomas (LSCCs) and Its Significance. Manuscript

Marta Grabowska, Katarzyna Michałek, Karolina Kędzierska-Kapuza, Andrzej Kram, Kamil Gill and Małgorzata Piasecka: The long-term effects of rapamycin-based immunosuppressive protocols on the expression of renal aquaporins 1, 2, 3 and 4 water channels in rats. Manuscript

Miguel A Ortega, Oscar Fraile-Martínez, Leonel Pekarek, Miguel A Alvarez- Mon, Ángel Asúnsolo, Lara Sanchez-Trujillo, Santiago Coca, Julia Buján, Melchor Álvarez-Mon, Natalio García-Honduvilla and Felipe Sainz: Defective expression of the peroxisome regulators PPARα receptors and lysogenesis with increased cellular senescence in the venous wall of chronic venous disorder. Manuscript

Emilio Lopez-Trujillo, Mònica Gonzàlez-Farré, Ramon M. Pujol, Beatriz Bellosillo, Roser Fisa, Cristina Riera, Magdalena Alcover, Carlos Barranco and Gemma Martin-Ezquerra: Diagnostic usefulness of immunohistochemical evaluation of CCD1a antigen and polyclonal anti-leishmania antibodies in cutaneous leishmaniasis. Manuscript

Mingqi Sun, Junli Yang, Dianming Jiang and Guoyu Bao: Overexpression of hsa_circ_0094742 inhibits IL-1β-induced decline in CHON-001 cell viability by targeting microRNA-127-5p. Manuscript

Chaoqun Huang, Yao Min, Jiuyang Liu, Jing Li and Xiaojun Yang: Ring Finger Protein 126: a potential biomarker for colorectal cancer. Manuscript

Ichiro Abe, Farhadul Islam, Chung Yau Lo, Victor Liew, Suja Pillai and Alfred K. Lam: VEGF-A/VEGF-B/VEGF-C expressions in non-hereditary, non-metastatic phaeochromocytoma. Manuscript

Flávia Emi Akamatsu, Walcy Rosolia Teodoro, Ana Maria Itezerote, Lizandre Keren Ramos da Silveira, Samir Saleh, Carlos Augusto Real Martinez, Marcelo Lima Ribeiro, José Aires Pereira, Flávio Hojaij, Mauro Andrade and Alfredo Luiz Jacomo: Photobiomodulation therapy increases collagen II after tendon experimental injury. Manuscript

Viera Almášiová, Katarína Holovská, Sandra Andrašková, Viera Cigánková, Zuzana Ševčíková, Adam Raček, Zuzana Andrejčáková, Katarína Beňová, Štefan Tóth, Eva Tvrdá, Ján Molnár and Enikö Račeková: Potential influence of prenatal 2.45 GHz radiofrequency electromagnetic field exposure on Wistar albino rat testis. Manuscript

Lena Haeberle, Andrea Cacciato Insilla, Anne-Christine Kapp, Katja Steiger, Anna Melissa Schlitter, Bjoern Konukiewitz, Ihsan Ekin Demir, Helmut Friess and Irene Esposito: Stroma composition and proliferative activity are related to therapy response in neoadjuvant treated pancreatic ductal adenocarcinoma. Manuscript

Alice Frosch, Sebastian Krohn, Gottfried Buchhorn, Wolfgang Lehmann, Karl- Heinz Frosch, László Füzesi and Stephan Frosch: Sequential osseointegration from osseohealing to osseoremodeling – Histomorphological comparison of novel 3D porous and solid Ti-6Al-4V titanium implants. Manuscript

Rhayanna B. Gaglianone, Flavia Fonseca Bloise, Jussara Lagrota-Candido, Claudia Mermelstein and Thereza Quirico-Santos: Persistent mdx diaphragm alterations are accompanied by increased expression and activity of calcium and muscle-specific proteins. Manuscript

Sang-Hwan Kim, Yong-Su Park, Da-Hye Shin, Jeong-Chan Moon, Min-Gee Oh and Jong-Taek Yoon: Porcine endometrial 3D co-culture: Morphological changes in 3D endometrium tissues according to hormonal changes. Manuscript

Jéssica Silvino Valente, Érika Stefani Perez, Bruna Tereza Thomazini Zanella, Tassiana Gutierrez de Paula, Sérgio Alexandre Alcantara dos Santos, Bruno Oliveira da Silva Duran, Robson Francisco Carvalho, Luis Antonio Justulin, Bruno Evaristo de Almeida Fantinatti and Maeli Dal-Pai-Silva: Maternal protein restriction changes structural and metabolic gene expression in the skeletal muscle of aging offspring rats. Manuscript

Jing-Yi Liu, Wen-Juan Lv, Jian-Bo Jian, Xiao-Hong Xin, Xin-Yan Zhao and Chun- Hong Hu: High-resolution three-dimensional visualization of hepatic sinusoids in cirrhotic rats via serial histological sections. Manuscript

Hui-juan Du, Su-xian Zhao, Wen Zhao, Na Fu, Wen-cong Li, Xiao-jie Qin, Yuguo Zhang, Yue-min Nan and Jing-min Zhao: Hepatic Macrophage activation and the LPS pathway in patients with different degrees of severity and histopathological patterns of drug induced liver injury. Manuscript

Junzhu Han, Jianzhong Guan and Xunbing Zhu: β-Ecdysone attenuates cartilage damage in a mouse model of collagenase-induced osteoarthritis via mediating FOXO1/ADAMTS-4/5 signaling axis. Manuscript

Stephan Frosch, Gottfried Buchhorn, Sebastian Krohn, Wolfgang, Lehmann, Karl-Heinz Frosch, László Füzesi and Alice Frosch: Osseointegration of a novel 3D porous Ti-6Al-4V implant material – Histomorphometric analysis in rabbits. Manuscript