HISTOLOGY AND HISTOPATHOLOGY

Cellular and Molecular Biology

 

Immunohistochemical expression of RECK protein in placental membranes of the preterm delivery with and without chorioamnionitis

Zdeslav Benzon1, Ivana KuzmiÁ Prusac2, Sandra Zekic2 and Marko Vulic1

1Department of Gynecology and Obstetrics and 2Institute for Pathology, University Hospital Split, School of Medicine, University of Split, Croatia

Offprint requests to: Marko Vulic, MD, Ph D, Department of Gynecology and Obstetrics, University Hospital Split, School of Medicine, University of Split,Spincica 1, 21 000 Split, Croatia. e-mail: marko.vulic1@st.t-com.hr


Summary. Objective: To compare the immunohisto-chemical expression of RECK protein in placental membranes of late preterm delivery in women with and without histologically proven chorioamnionitis. Study design: Fetal membranes were collected from women who had late preterm delivery with (n=8) and without (n=9) histologic chorioamnionitis. Immuno-histochemistry for RECK protein was performed on formalin fixed and paraffin-embedded sections. The two groups were matched for age, body mass index and parity. SPSS Version 13.0 was used for statistical analysis. Results: There was weaker immunohistochemical expression of RECK protein in placental membranes of women with histologic chorioamnionitis compared to control subjects (P=0.0498). Conclusions: Chorioamnionitis has an impact on immunohistochemical expression of RECK protein in placental membranes in late preterm delivery. Histol Histopathol 29, 629-633 (2014)

Key words: Late preterm delivery, Placental membranes, Immunohistochemical expression, RECK protein

DOI: 10.14670/HH-29.10.629