HISTOLOGY AND HISTOPATHOLOGY

Cellular and Molecular Biology

 

Review

Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis. A narrative review

Giuseppe Musumeci1, Carla Loreto1, Rosa Imbesi1, Francesca Maria Trovato2, Angelo Di Giunta3, Claudia Lombardo1, Sergio Castorina1,3 and Paola Castrogiovanni1

1Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, Italy, 2Department of Medical and Pediatric Sciences, Internal Medicine Division, University of Catania, Italy and 3Fondazione Mediterranea ‘‘G.B. Morgagni’’, Catania, Italy

Offprint requests to: Dr. G. Musumeci Ph.D, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, Italy. 95123 Catania, Italy. e-mail: g.musumeci@unict.it


Summary. Knee osteoarthritis (OA) represents one of the most common causes of disability in the world. It leads to social, psychological and economic costs with financial consequences, also because a further increase is expected. Different knee OA treatments are usually considered in relation to the stage of the disease, such as surgical management and pharmacologic and non-pharmacologic treatments. Treatment should begin with the safest and least invasive one, before proceeding to more invasive, expensive ones. Non-pharmacologic, behavioral treatments of knee OA are recommended not only in rehabilitation but also in prevention because many risk factors, such as excess weight, obesity and joint tissue inflammation, can be monitored and thus prevented. In the present review, we analyze data from the most recent literature in relation to the effects of physical exercise on prevention, therapy and rehabilitation in knee OA. All data suggest that physical exercise is an effective, economical and accessible tool to everyone, in the treatment and prevention of knee OA. The literature search was conducted on PubMed, Scopus and Google Scholar using appropriate keywords in relation to knee osteoarthritis. Histol Histopathol 29, 707-719 (2014)

Key words: Knee osteoarthritis, Exercise, Rehabilitation, Prevention

DOI: 10.14670/HH-29.707