HISTOLOGY AND HISTOPATHOLOGY

Cellular and Molecular Biology

 

Review

Treatments of the injured tendons in Veterinary Medicine: from scaffolds to adult stem cells

Marco Patruno and Tiziana Martinello

Department of Comparative Biomedicine and Food Science, Università di Padova, Agripolis, Italy

Offprint requests to: Marco Patruno, Department of Comparative Biomedicine and Food Science, Università di Padova, Agripolis, Viale dell'Università, 16, 35020 Legnaro (PD), Italy; e-mail: marco.pat@unipd.it


Summary. In order to treat frequently occurring conditions such as traumatic rupture or over-strain tendinopathies, the techniques of tissue engineering and cell-based therapies have become an accepted modus operandi since other available remedies appear to be ineffective in restoring the original structure and function of the injured tissue. However, the mechanisms accounting for the effectiveness of novel regenerative approaches in treating equine tendon and ligament injuries remain poorly characterised. In this review we summarize and discuss the most significant results of our research regarding bioscaffold technology for treating complete tendon tears and the use of adult stem cells for treating tendon lesions induced by over-strain
. Histol Histopathol 29, 417-422 (2014)

Key words: Bioscaffold, Mesenchymal stem cells, Tendon injuries

DOI: 10.14670/HH-29.10.417